The Gifted is Marvel`s world set in an alternate universe of the one X-men inhabited.
In this world, X-men are gone.
The Gifted is more intimate and revolves around characters who don`t know (yet) that they are mutants.
Constant problems with society and the world around them and difficulties that mutants undergo while trying to fit in are what makes this show shines.
A show is not over the top with special effects and action but rather subtle and more personal, and it’s just a perfect formula.